Understanding Strep Throat: Signs, Symptoms, and Causes

Strep throat (caused by Group A Streptococcus) typically comes on suddenly — severe sore throat, painful swallowing, fever usually over 101°F, tonsils swollen with white or yellow patches or pus, tender lymph nodes in the front of the neck, and characteristically the absence of cough, runny nose, or hoarseness. Small red spots on the soft palate are sometimes visible. Viral sore throat (the most common cause, 70-85% of cases) is gradual, milder, comes with cough, runny nose, red eyes and hoarseness, and shows diffuse throat redness without pus. Doctors use the Centor criteria — fever, absence of cough, tender anterior neck lymph nodes, tonsillar exudate — with 3-4 features suggesting bacterial infection and warranting a test. Age matters: strep is more common in children 5-15 and less common in adults. Diagnosis uses a Rapid Antigen Detection Test (result in 10 minutes) or throat culture (gold standard, 24-48 hours). Every confirmed strep should be treated — to prevent rheumatic fever complications.

First-line treatment is Penicillin V (Phenoxymethylpenicillin) 500 mg orally 2-3 times daily for 10 days (children: 250 mg twice daily) — cheap and highly effective. Amoxicillin at 500 mg three times daily for 10 days is an alternative (often preferred for children because it tastes better). For penicillin allergy, use Cephalexin, Azithromycin (5 days), or Clarithromycin. In severe cases or when adherence is a concern, a single intramuscular Benzathine Penicillin G injection is an option — also used for rheumatic fever secondary prophylaxis. Complete the full 10 days even after feeling better — incomplete courses allow bacteria to survive and dramatically increase rheumatic fever risk (which can permanently damage heart valves). Supportive care: warm salt-water gargles, paracetamol or ibuprofen for fever and pain, adequate fluids and rest, soft cold foods, and avoid smoking. You're no longer contagious 24 hours after starting antibiotics. Household spread is common (25-40% of contacts) — test any symptomatic family members. If you have more than 3 episodes a year, consider ENT evaluation for tonsillectomy.

Untreated or under-treated strep can cause serious complications. Rheumatic fever, 1-3 weeks after infection, is an immune reaction affecting joints, heart, brain and skin; it causes rheumatic heart disease — still the leading cause of acquired heart disease in Indian children (with prevalence around 1-5 per 1000 school children) — and permanently damages heart valves. It's entirely preventable with a timely 10-day antibiotic course. Post-streptococcal glomerulonephritis affects the kidneys 1-3 weeks after infection with inflammation, blood in urine, and high blood pressure. Peritonsillar abscess (quinsy) is a pus collection behind the tonsil, with severe pain, drooling, muffled voice and inability to open the mouth fully — needs urgent ENT drainage. Scarlet fever presents with a sandpaper rash and strawberry tongue. Deep neck-space abscesses are medical emergencies. In children, rare neuropsychiatric syndromes (PANDAS/PANS) can follow strep. The India-specific concern is the ongoing rheumatic heart disease burden — every child with possible strep throat should be tested and treated properly.