Diabetes Complications

Chronically high sugar damages small and large blood vessels. Small-vessel damage causes retinopathy (eyes), nephropathy (kidneys), and neuropathy (nerves). Large-vessel damage speeds up atherosclerosis, causing heart attack, stroke, and poor blood flow to the legs. Complications develop silently over 5-15 years — usually before symptoms appear — which is why routine screening tests matter more than waiting for something to hurt.

Every diabetic adult needs a dilated retinal examination by an ophthalmologist within 5 years of type 1 diagnosis (or at diagnosis for type 2), then annually. Early diabetic retinopathy has no symptoms — by the time you notice blurred vision, damage is often advanced. Laser treatment and newer anti-VEGF injections prevent blindness when caught early. Don't skip the yearly eye check even if your vision feels fine.

Annually — a urine test for microalbumin (protein leak) and a blood test for creatinine (kidney filtration). Microalbumin appears years before creatinine rises, giving a warning window when ACE inhibitors or ARBs (a class of blood pressure medications) can slow damage significantly. Poor sugar control, high blood pressure, and smoking all speed nephropathy — controlling these three is the single most important thing to protect kidneys.

Diabetic neuropathy starts with numbness, tingling, or burning in the toes and feet, gradually working upward — 'stocking-and-glove' pattern. It's often worse at night. Once nerves are damaged, sensation is reduced, so small injuries (a stone in the shoe, ill-fitting sandals, a cut trimming a toenail) go unnoticed and become infected. Daily foot inspection, well-fitting footwear, moisturized skin, and prompt doctor visits for any wound are the pillars of preventing foot ulcers and amputations.

Yes — even people with diabetes for 20+ years often have no complications if they've maintained good control. The pillars: HbA1c under 7% (or your individualized target), blood pressure under 130/80, LDL cholesterol under 100, no smoking, annual eye/kidney/foot examinations, and prompt treatment when anything abnormal appears. Complications are largely a function of years of poor control — not diabetes itself.